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Alexander Spirin was an eminent Russian biochemist, who was one of the early pioneers in ribosome research. His lifelong research interests were nucleic acids and protein synthesis. Among his many early achievements he predicted the existence of messenger RNA, and showed that the RNA content of ribosomes does not code for protein, but is structural in nature. He had deep insights It has been proposed that ribosomes are catalytic engines capable of changing their protein composition in response to environmental stimuli.
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